Orpheus is a key Persona in the video game and anime series 'Persona 3.' As the initial Persona of the protagonist, Orpheus represents beginnings and transformation, drawing inspiration from the mythological Greek musician Orpheus. In the story, Orpheus emerges during the protagonist’s first summoning, symbolizing their journey into the world of Shadows and Personas. Orpheus serves as a vital companion in battles and narrative, embodying the potential and growth of the main character throughout the series.